This gzipped tar archive contains the latest version (Release 2-2.16) of the Purkinje cell tutorial, and can be used to replace Release 2-2.11, which is included in the GENESIS 2.3 genesis/Scripts/purkinje directory. The tutorial implements the full De Schutter and Bower (1994) detailed Purkinje cell model. It extracts to the directory "Purkinje_tutorial", so that it will not overwrite the older version, if it is unpacked in the genesis directory. In the new version, multiple cell views are now possible via the output menu, and a configuration layer on top of the tutorial allows you to restrict the GUI to the things that you think are important. The files README and help.txt (which can be viewed with the HELP button) describe the model and the various types of synaptic input that you can apply.
These two tutorials, in the subdirectories tutorial7 and tutorial8, were written by Rick Jensen and Mike Vanier for the 1995 Methods in Computational Neuroscience course at Woods Hole. Their purpose is to extend the six tutorials in the genesis/Scripts/tutorials directory to cover the construction and visualization of networks of neurons. More detailed descriptions of the commands for building networks are provided in Chapter 17 of the Book of GENESIS and in the GENESIS Reference Manual.
tutorial7:
The goal of this tutorial is to set up a two-dimensional array of model neurons with local excitatory and long-range inhibitory connections. This is easily accomplished using GENESIS by creating prototype elements with cell bodies, ion channels, and spike-generating elements which are duplicated, assigned positions in a two-dimensional grid, and graphically displayed. The text of the tutorial is given in tutorial7.text, and the script used to run the tutorial is tutorial7.g.
tutorial8:
In this tutorial we adapt the network in tutorial 7 to solve a famous optimization problem, the eight queens problem. This is done with a network of simple, but biologically realistic spiking neurons. The text of the tutorial is given in tutorial8.text, and the script used to run the tutorial is tutorial8.g.
The simulation CPG_Rev, contributed by Joseph Aulenbrock, is a modification of the CPG tutorial, intended to extend its use to the study of simple idealized Hebbian reverberations. The documentation, in the text file reverb.txt and the postscript file reverb.ps, explores the behavior of some examples.
An improved version of revpac. The postprocessing has been simplified, and references have been added in the documentation.
These files were submitted by Ed Vigmond and were used in a biomedical engineering bio-electricity course at the University of Toronto. They contain scripts and excercises to accompany the Squid and Cable tutorials.
This is a Mini-Tutorial on Voltage Clamp Circuitry Tuning, with suggested strategies for "tuning" the circuitry parameters to achieve a balance of the quality of the voltage clamp against the size of the integration time step.