This set of exercises was used at the Latin American School on
Computational Neuroscience (LASCON) to get students to the point
of quickly creating cell models.
- Chapt. 7 - Ion Channels and Bursting Neurons
- V and Ca activated channels
- Case study of genesis/Scripts/burster model
- Neurokit experiments with genesis/Scripts/traub91
- Chapt. 19 (1st ed: 18) - Implementing Other Types of Channels
(Use of tabchannels)
- Chapt. 16 (1st ed: 15) - Cell Construction with the Cell Reader
- Chapt. 17 (1st ed: 16) - Building a Cell With Neurokit
- Chapt. 20 (1st ed: 19) - Last part: using hsolve
Pick an intresting neuron for which (ideally):
- There is no GENESIS model
- Important channels have been identified
- Some voltage clamp data is available
- Some current clamp data is available
THEN
- Make simplifed morphology ("ball and stick" or "reduced morpholgy")
- Implement channels
- starting from scratch, or
- modifying existing GENESIS channels (Scripts/neurokit/prototypes
- Perform parameter seach
- manually (possibly with Neurokit)
- automatically (see Reference Manual "Parameter Search Library")